Glucosamine and Chondroitin

Glucosamine and Chondroitin

Both glucosamine sulfate and chondroitin sulfate belong to a class of compounds called glycosaminoglycans. Glucosamine furnishes the basic building block of mucopolysaccharides which is the integral components of synovial fluid that form the framework of bones, cartilage, nails, hair and skin. Increased amounts of glucoasamine stimulates the activity of specialized cells called chondrocytes. These cells then build the framework of bone and cartilage with mucopolysaccharides.

Chondroitin sulfate act as bait, attracting fluid into the web like cartilage that covers the bone of the joint. The fluid attracted into the cartilage provides shock absorption for surrounding bones and supplies nutrients to the cartilage, thus supporting its regeneration and growth. Joint cartilages does not possess a blood supply, so its nutritional needs must be meet by the fluid surrounding the joint.

Supplemental sources of glucosamine is available in three forms: sulfate, hydrochloride and n-acetyl, but glucosamine sulfate has been studied the most. Chondroitin is available in animal tissues such as gristles around joints. Chondroitin works synergistically with glucosamine to prevent premature breakdown of cartilage and stimulate production of new cartilage.

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