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Both
glucosamine sulfate and chondroitin sulfate belong to a class of
compounds called glycosaminoglycans. Glucosamine furnishes the basic
building block of mucopolysaccharides which is the integral components
of synovial fluid that form the framework of bones, cartilage, nails,
hair and skin. Increased amounts of glucoasamine stimulates the activity
of specialized cells called chondrocytes. These cells then build the
framework of bone and cartilage with mucopolysaccharides.
Chondroitin
sulfate act as bait, attracting fluid into the web like cartilage that
covers the bone of the joint. The fluid attracted into the cartilage
provides shock absorption for surrounding bones and supplies nutrients
to the cartilage, thus supporting its regeneration and growth. Joint
cartilages does not possess a blood supply, so its nutritional needs
must be meet by the fluid surrounding the joint.
Supplemental
sources of glucosamine is available in three forms: sulfate,
hydrochloride and n-acetyl, but glucosamine sulfate has been studied the
most. Chondroitin is available in animal tissues such as gristles around
joints. Chondroitin works synergistically with glucosamine to prevent
premature breakdown of cartilage and stimulate production of new
cartilage.
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