Overuse may result in tenosynovitis, an inflammatory condition of the synovium which lines a tendon sheath and surrounds the tendon. One of the most common examples is bicepital tenosynovitis, which involves the tendon of the long head of the biceps brachii, in the bicepital groove of the shoulder.

The early symptom is shoulder pain, which may be present only with motion as the tendon passes back and forth in its sheath, or may be constant and occur even at rest.

In the early stages, treatment is the same as for muscle strain: rest, moist heat and protection against further injury. In the very acute stage, injection of corticosteroid may also be required. In advanced stages, the complications are serious and surgery may be required.

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