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Amino guanidine has certainly been used
to prevent cataract, arthritis, osteoporosis, wrinkles and other
age-related illnesses. Amino guanidine has also been used by diabetics to try and
reduce the damage related to too much glucose in the blood. Amino
guanidine doesn't
reverse existing damage, but does prevent further cross-linking.
During normal aging, sugar molecules in
the body react violently with proteins, causing them to malfunction.
This process is called glycosylation (or glycation) of proteins. The
chemical leftover products from this lethal encounter are called AGEs
(advanced glycation end products).
Glycosylation causes cross-linking of
collagen, enzymes and other proteins as well as damage to the DNA.
Cross-linking is an abnormal process during which proteins attach to
each other as if they have been plastered with glue, becoming stiff and
unnaturally twisted. Generally, these abnormal proteins are immediately
removed from the body, but with age this removal becomes sluggish as the
body wears out, allowing abnormal proteins to pile up.
Cross-linked proteins are found in
diabetes, Alzheimer's dementia and in many other diseases of aging. For
example, AGEs
(advanced glycation end products) are blamed for causing:
Too many AGEs
(advanced glycation end products) in the blood is a sign that the rate
of aging is speeding up beyond control. AGEs
(advanced glycation end products) make you age.
Certain chemicals can put a stop to the
production of AGEs. One of these is amino guanidine, another is
carnosine. Treatment with amino guanidine is believed by some
specialists to stop aging before it even starts.
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